ferroportin

• 铁转运蛋白（生物学术语）
• 运铁素（生物学术语）

The ferroportin disease
The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis.
The molecular mechanism of hepcidin-mediated ferroportin down-regulation.
Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages.
Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization
Presence of the iron exporter ferroportin at the plasma membrane of macrophages is enhanced by iron loading and down-regulated by he...
Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene
Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs
Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin
Montosi, G. et al. Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene. J. Clin. Inve...